BRNZ Principal and Associate Investigators

University of Otago – Dunedin

BRNZ_Otago PIs

Prof Cliff Abraham (Theme 1, 2, 3) - Neural mechanisms of learning and memory, cellular and molecular events underlying nervous system plasticity and Alzheimer’s disease. Expertise in electrophysiological, behavioural and immunofluorescent microscopy approaches to studying the mechanisms mediating the induction and persistence of synaptic plasticity in vivo and in vitro, and their relevance to memory. Blood biomarkers of Alzheimer’s disease.

 

Assoc Prof Lubica Benuskova (Theme 2, 3) - Neurobiologically inspired computing and dynamics of biological and artificial neural networks, including learning rules, spiking neural networks, classification and prediction by means of neural networks and computational neurogenetic modelling (investigating the dynamic influence of internal gene regulatory networks on neural dynamics). Also Cognitive Science, Cognitive Neuroscience and applications of Computational Intelligence in Bioinformatics.

 

Assoc Prof Michael Black (Theme 2) - Analysis of data from gene expression microarray experiments, Bayesian statistical methods, and statistical computing.

 

Dr Andrew Clarkson (Theme 1, 3) - Post-stroke neuroprotection and regeneration and repair mechanisms promoting recovery of function following a stroke involving novel combinations of intensive rehabilitation, drug therapy and more recently stem cells to enhance brain repair processes. This utilises behavioural, electrophysiological, optical imaging and anatomical measures to assess recovery after stroke.

 

Dr Nick Cutfield (Theme 4) - Developing predictive blood biomarkers for Alzheimer’s; Vestibular schwannoma; Relationship of high frequency eye movement recordings to cognition and balance in Parkinson’s disease; Augmented reflection technology in neurorehabilitation.

 

Assoc Prof Ruth Empson (Theme 1) - Cellular and network identity in the motor cortex, Cerebellar circuitry; Movement disorders including ataxia, motor neurone disease and spinal injury; Contribution from the cerebellum to cognitive processes and its disruption in the poorly treated disorder autism. A combination of electrophysiology, live imaging and molecular approaches are used.

 

Prof Leigh Hale (Theme 4) - Clinical neurorehabilitation; Fall prevention in older adults and adults with intellectual disabilities, Parkinson’s disease and Alzheimer’s disease; Use of virtual reality in stroke rehabilitation; facilitating Self-management following stroke, Measuring physical activity with accelerometry in people with neurological dysfunction; facilitating physical activity in people with disability.

 

Dr Stephanie Hughes (Theme 1, 3) - Identifying molecular pathways that regulate neuronal development, maintenance and disease; Transcription factors of the forebrain embryonic zinc finger family and their role in neuronal development and maintenance; and on the molecular consequences of mutations in Batten disease, a childhood neurodegenerative disorder. Developing tools and gene therapy vectors for Batten disease as well as Alzheimer’s and Parkinson’s disease. Development and packaging of novel lentiviral and AAV vectors.

 

Prof Brian Hyland (Theme 1) - Neurophysiology of midbrain dopamine systems and pathways which modulate dopamine neuron activity. Effects of abnormal dopamine activity, such as occurs in Parkinson's disease, on activity in the motor control pathways.

 

Assoc Prof Steve Kerr (Theme 1) - Pharmacological preconditioning; CNS neuroprotection and the super-sensitivity of the aged brain to excitotoxic insult; cardiac damage following seizures (SUDEP). Using electrophysiological, anatomical, behavioural and molecular approaches.

 

Assoc Prof Ping Liu (Theme 1, 2, 4) - Neurobiological basis and intervention of cognitive decline associated with aging and Alzheimer's disease, as well as schizophrenia; Biological basis of learning and memory. Expertise in a combination of behavioural, in vivo microdialysis, neurochemical, molecular biological, immunohistochemical and electrophysiological approaches.

 

Dr Liana Machado (Theme 3, 4) - Neuropsychology and cognitive psychology expert. Her research investigates cognitive deficits that emerge as a result of brain disease and healthy aging, and methods by which these deficits can be minimized via simple accessible methods.

 

Prof Ian McLennan (Theme 1) - Neurodegenerative disorders; Sexual differentiation of the brain; Cognitive development of children. Investigating the role MIS/AMH plays as a multi-dimensional regulator of the brain, with very distinct actions that vary with the stage of the life cycle. A broad range of molecular, cellular and whole animal techniques are used.

 

Prof Pauline Norris (Theme 4) - Research focuses on access to, and use of, medicines. Particular interest in how lay people understand and use medicines, and looking at particular population groups and barriers they face in accessing and using safe and appropriate medicines. I use both qualitative and quantitative research methods. Research in the Pacific and with Pacific people in New Zealand, medicines use in Tairawhiti, medications in everyday life.

 

Dr Louise Parr-Brownlie (Ngāti Maniapoto, Ngāti Pikiao; Theme 1, 3) - Neural mechanisms underlying voluntary movements and the movement deficits of Parkinson's disease. Motor thalamus and motor cortex function are being explored using cutting-edge optogenetic technology that enables characterisation and manipulation of part of the basal ganglia-thalamocortical pathway. Optogenetic modulation of brain activity in an animal model of Parkinson's disease to learn how this alters motor thalamus and motor cortex activity, and behaviour. Electrophysiological, behavioural and immunohistochemical techniques.

 

Prof Richie Poulton (Theme 2) - Developmental psychopathology, gene X environment prediction of complex disorders, and psychosocial determinants of chronic physical disease. Dunedin Longitudinal Study.

 

Assoc Prof Holger Regenbrecht (Theme 3) - Human-Computer Interaction (HCI), Augmented reality, 3D Teleconferencing, psychological aspects of Mixed Reality, three-dimensional user interfaces (3DU) and computer-aided therapy and rehabilitation.

 

Assoc Prof John Reynolds (Theme 1, 3) - Learning and memory mechanisms in the basal ganglia and cortex in the mammalian brain, with a particular focus on normal and disordered synaptic mechanisms in Parkinson's disease and stroke. Expertise in electrophysiological recording, neurostimulation and neuromodulation (using electrical and transcranial magnetic stimulation), molecular biology, immunohistochemistry and operant behaviour.

 

Prof Dirk De Ridder (Theme 1, 3) - Pathophysiological mechanisms clustering groups of pathologies, such as thalamocortical dysrhythmias (pain, tinnitus, epilepsy, depression, Parkinson's disease, schizophrenia) or obsessive compulsive spectrum disorder; clinical neuromodulation; and neural correlates of the “self” how the self is generated in the brain, its relation to the environment (eg of importance in MCI and dementia), to others and god. Expertise in interpreting functional imaging data (PET, fMRI, EEG, MEG), and the application of non-invasive neuromodulation techniques (TMS, tDCS, tRNS, tACS, EEG feedback) and invasive brain implantation techniques.

 

Prof Ted Ruffman (Theme 4) - Social understanding in infants, children and in young and older adults; whether emotion recognition, understanding of social gaffes, and the ability to detect a lie deteriorate in older adulthood; gambling behaviour in older adults.

 

Dr Jon Shemmell (Theme 1, 3) - Contribution of neural adaptation to exercise-related improvements in arm and hand control; development and optimisation of movement rehabilitation techniques for stroke survivors; improving stroke rehabilitation methods using advanced sensory and motor stimulation techniques to induce neural adaptations beneficial to motor learning and recovery. Identifying neural structures involved in the regulation of spinal reflex excitability and abnormal muscle coupling; determining the effects of prolonged sensory stimulation on cortical adaptations during learning and stroke rehabilitation; and optimising a painless, non-invasive brain stimulation technique that has shown promise as a tool for enhancing motor learning and stroke rehabilitation.

 

Prof Paul Smith (Theme 1, 3) - Vestibular and auditory systems; Vestibular dysfunction and tinnitus; Effects of vestibular damage on the hippocampus; effects of cannabis on the brain; and applications of statistics to pharmacology. The effects of vestibular and auditory damage on the brainstem vestibular and cochlear nuclei, and other areas of the CNS such as the cerebellum and medial temporal lobe.

 

Prof Warren Tate (Theme 1, 2) - Understanding protein synthesis and, in particular, decoding and recoding mechanisms on the ribosome at stop signals; molecular mechanisms of mammalian memory and how they are impaired in human neurological diseases, particularly Alzheimer’s.

 

Prof Ian Tucker (Theme 1) - Delivery systems for optimal delivery of bioactives; Absorption processes to achieve optimal delivery of bioactives to target organs/cells. Expertise in cell culture studies, electron microscopy, in vivo studies including microdialysis, analytical methods (LCMS, radiotracer). 

 

Dr Joanna Williams (Theme 1, 2) - Understanding the molecular steps involved in memory formation, maintenance of memories and identifying how these are perturbed in disease. Expertise in modern molecular biological, bioinformatics and proteomic techniques focused on the regulation of key glutamate receptors and how gene expression is altered in response to memory events.

 

Dr Yiwen Zheng (Theme 1, 3) - Understanding the underlying mechanisms of tinnitus and developing target-specific therapies through drugs and brain stimulation techniques. Expertise in a range of biochemical, electrophysiological and behavioural approaches.

 

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University of Canterbury

BRNZ_university-canterbury-campusstudents

Prof John Dalrymple-Alford (Theme 2, 3, 4) - Neuropsychology, including disorders of memory; neurodegenerative disorders; recovery of function after brain damage; Behavioural Neuroscience, including animal models of the effects of brain damage in humans; neural transplants; hippocampal system function; enriched environments; Behavioural pharmacology.

 

Prof Tim David (Theme 2) - Mathematical and numerical models of cerebral autoregulation, neurovascular coupling, and cardiovascular blood flow.

 

 

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University of Otago - Christchurch

BRNZ_Tracey Meltzer

Prof Tim Anderson (Theme 1, 2, 3, 4) -  Human movement and oculomotor disorders, with  particular focus on Parkinson’s and Huntington’s disease; Identification of biomarkers, and predictors, of  cognitive impairment in Parkinson’s disease.  Identification and treatment of mild cognitive impairment  as a pre-Alzheimer’s state.

 

Dr Tracy Melzer (Theme 2) - Brain development and other neurological conditions, including Parkinson's disease. Expertise in MRI.

 

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Auckland University of Technology

BRNZ_Valery Feigin

Prof Valery Feigin (Theme 4) - Stroke and Traumatic Brain Injury prevention, epidemiology and treatment/rehabilitation; neuroepidemiology

 

Assoc Prof Nicola Kayes (Theme 4) - Explores the intersection between health psychology and rehabilitation, aiming to challenge conventional rehabilitation practice through the development of innovative strategies to engaging in rehabilitation. Her key research interests include an exploration of factors influencing engagement in rehabilitation (including the role that health professionals play), the development of innovative strategies for facilitating engagement for people with chronic disabling conditions, and the development of outcome measures responsive to the needs of people engaging in the rehabilitation process. 

 

 

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University of Auckland

Prof Richard Faull (Ngāti Rahiri, Te Atiawa; Theme 1, 2, 3) - Molecular biological and anatomical studies on the chemical changes in the following major neurodegenerative diseases of the human brain – Huntington’s disease, Alzheimer’s disease, schizophrenia, Parkinson’s disease, epilepsy and Motor Neuron disease. Clinical profile and chemical anatomical pathology and genotype in HD to determine whether variations in clinical symptomatology are reflected by variations in the chemical pathology and HD gene. Establishment of a transgenic sheep model of Huntington's disease. Molecular mechanisms and patterns of nerve cell death and repair in neurodegenerative diseases focusing on the role of transcription factors and growth factors, and using in vitro cell culture models, and transgenic animal models. Investigations on the potential of various novel methods to treat neurodegenerative diseases including gene therapy techniques (decoy DNA, antisense DNA, peptide nucleic acids), and neurotrophins to prevent neuronal death in neurodegenerative diseases. Neurogenesis in the human brain including whether stem cells in the adult human brain and spinal cord have the ability to proliferate and form new neurons in response to brain injury and disease, pathways of neurogenesis in the human brain, mechanisms involved in the induction of neurogenesis, and whether stem cells have the potential to ‘repair’ the injured or diseased adult brain and spinal cord.

 

Assoc Prof Donna Rose Addis (Theme 2, 3) - Combining neuroimaging, behavioural and neuropsychological methods to investigate how the brain remembers past experiences, how we use memory to simulate future events and construct a sense of identity, and how these abilities change in healthy ageing and dementia. The role of the hippocampus in memory, and research with populations with hippocampal dysfunction, including Alzheimer’s disease, temporal lobe epilepsy and depression.

 

Prof Toni Ashton (Theme 4) - Funding and organisation of health services from an economic perspective. Research on various aspects of health reform in New Zealand over the past two decades. Study of comparative health systems and in the general application of economic theory and methods to health sector practices and performance.

 

Assoc Prof Suzanne Barker-Collo (Theme 4) - Clinical neuropsychology with interest in traumatic brain injury neuropsychological assessment and rehabilitation, post-stroke cognition and mood.

 

Prof Alan Barber (Ngāti Porou, Whakatōhea; Theme 3, 4) - Clinical neurology, stroke specialist. Research interests include the use of advanced neurophysiology and MRI techniques in stroke.

 

Assoc Prof Nigel Birch (Theme 1) - Applying molecular and cellular approaches to identify the molecules and signalling pathways involved in neuronal differentiation, cellular communication and synaptic plasticity in the nervous system and how these are perturbed in disease. Studies of immune cell migration and function linking to neuroinflammation. Cell-based models of protease and protease inhibitor regulation of extracellular protein processing.  Links to Alzheimer’s disease and schizophrenia.  Application of reprogramming and gene knock-in/out technologies to generate novel disease models.

 

Prof Margaret Brimble (Theme 1) - Synthesis of novel peptide hormones and proteins especially peptides derived from neurotrophins. Construction of peptide-based drugs engineered to improve pharmaceutical performance. Synthesis of complex bioactive natural products using asymmetric synthesis, heterocyclic chemistry and organocatalysis. Peptide chemistry, with two peptide-based drug candidates now in clinical trials. Synthesis of complex glycopeptides, lipopeptides, labelled peptides, peptidomimetics and long peptides. Rigorous structure determination using nuclear magnetic resonance, mass spectrometry and X-ray crystallography. Synthesis and screening compounds from natural product library using Biobank tissues.

 

Prof Winston Byblow (Theme 1, 3) - Neural control of movement in health and disease, including ways to enhance motor recovery after stroke, and improve movement abilities of people with movement disorders. Expertise in neuroplasticity assessment, functional MRI, noninvasive brain stimulation, electromyography.

 

Assoc Prof David Christie (Theme 1) - Molecular and cellular approaches to identify fundamental mechanisms by which neurons function. Regulation of nutrient uptake and mitochondrial function in relation to supplying the energy required for ongoing activity of neurons. Cell based models of the creatine transporter, and why cerebral creatine deficiency results in intellectual disability. The structure and function of membrane transporters, receptors and ion channels.  Links between clusterin, ApoE, inflammation and Alzheimer’s disease. Application of reprogramming and gene knockin/out technologies to generate novel disease models.

 

Assoc Prof Bronwen Connor  (Theme 1, 3) - Gene therapy for Parkinson’s disease and Huntington’s disease; development of stem cell replacement therapy for Parkinson’s disease, Huntington’s disease and stroke; identification of novel agents for the treatment of depression. Biological function and role of neural stem cells in the adult brain, and the response of neural stem cells to brain injury or disease. Somatic cell reprogramming of adult human fibroblasts to produce neural precursor cells for disease modelling, drug-screening and cell replacement strategies.

 

Prof Garth Cooper (Ngāti Mahanga, Tainui; Theme 2) - Discovery of novel peptide hormones and proteins, detailed functional analysis of purified proteins in cellular and whole animal models and human systems. Construction of peptide-based drugs and development of proteins with functions engineered to improve pharmaceutical performance. Defining new drugs and drug targets, based upon the identification of new proteins and physiological processes. The metabolic basis and experimental therapeutics of Alzheimer's disease and Huntington's disease.

 

Assoc Prof Maurice Curtis (Theme 1, 3) - Mechanisms of stem cell proliferation in neurodegenerative diseases. Understanding the regulation of stem/progenitor cell migration in the brain at the molecular and cellular level. Plasticity in the Alzheimer’s and Parkinson’s brain. Early origins of neurodegenerative diseases with an emphasis on Alzheimer’s disease and Parkinson’s disease. Deputy Director of the NFNZ Human Brain Bank

 

Prof Mike Dragunow (Theme 1, 2) - Molecular mechanisms of human brain neurodegeneration and repair and development of novel treatments for brain diseases using adult human brain material, tissue microarray, cell culture models (cell lines and primary adult human brain cultures), molecular pharmacology and high-content analysis. Understanding causes of human neurodegeneration and testing and development of new treatment strategies.

 

Dr Jian Guan (Theme 1) - Biological function of insulin-like growth factor-1 and its metabolites in preventing and improving the recovery from acute injuries and in chronic neurological conditions in neonatal, infant, young adult and aging brains. Effects of nutrition on brain development, premature aging and cognitive function; vascular degeneration and remodeling in neurological conditions and recovery.  Animal based experiments and models, behavioral testing, neuronal anatomy, neurobiology and pharmacology.

 

Prof Ngaire Kerse (Theme 2, 4) - Maximising health for older people by studying the pathway from impairment to dependence with a particular interest in the very old and those with dementia in all settings. The LILACS NZ cohort study examines predictors of successful advanced ageing in Māori and non-Māori. A mix of clinical, health services and public health research aims to improve care and outcomes for older people. In the CORE, development and testing of interventions delivering dual cognitive and physical training to prevent progression of MCI is a priority and examining predictors of progression of cognitive decline in the very old. Establishment of the dementia clinics is also a priority.

 

Prof Ian Kirk (Theme 1, 2, 3) - Neural systems involved in memory and attentional processes, and the genetic mechanisms that modulate these systems such as BDNF and COMT. Functional (EEG and fMRI) and structural (DTI) imaging to investigate the temporal and spatial neurodynamics, and the anatomical substrates, of cognitive processes. Atypical processing in a number of disorders including Alzheimer’s and Parkinson’s disease.

 

Prof Janusz Lipski (Theme 1) - Cellular and molecular mechanisms of neuronal damage in models of Parkinson’s disease and stroke. Physiology and pathophysiology of dopaminergic neurons in the Substantia Nigra, and pyramidal neurons in the hippocampus. Cellular effects of neurotoxins, L-DOPA, psychostimulants and TRP channel activation. Neuroprotective role of glutamate transporters and antioxidants. In vitro models (acute brain slices and organotypic slice culture), electrophysiology, calcium imaging, measurement of cell swelling, ROS production, immunocytochemistry/western blots, receptor pharmacology and optogenetics.

 

Assoc Prof Johanna Montgomery (Theme 1) - Molecular mechanisms that underlie the physiology of excitatory synapses in the brain combining electrophysiology, molecular biology and imaging techniques to investigate how changes in synapse function could underlie developmental disorders such as Autism, and neurodegenerative disorders such as Huntington's Disease and hearing changes.

 

Prof Louise Nicholson (Theme 1) - Investigating the role of inflammation in neurodegeneration, spinal cord injury and repair, cancer and other diseases.  Molecular mechanisms of degeneration in neurodegenerative diseases that have a late onset. The role of gap junctions in central nervous system diseases and injury.

 

Prof Cris Print (Theme 2) - Use of bioinformatics to improve our understanding of pathology. Bringing bioinformatic information together with clinicopathological information and traditional cell biology/transgenic studies.

 

Prof Suzanne Purdy (Ngāti Takoto, Te Rarawa; Theme 3, 4) - Communication and cognition in adults and children with auditory and neurological dysfunction (including auditory processing disorder, Parkinson’s disease, stroke/aphasia  and autism). Research areas include speech perception and production, language, affective prosody and auditory processing. Techniques include behavioral assessment of cognition, perception and wellbeing and electrophysiological evaluation of auditory and language processing function across the lifespan. Recent studies have examined music based (choral singing) therapies for people with neurological disease (aphasia & Parkinson’s disease) and emotional word based therapy for people with aphasia.

 

Dr Grant Searchfield (Theme 1, 3) - Hearing and deafness, Hearing aids, Auditory cognitive processes and training, Mechanisms of tinnitus assessment and management of tinnitus, , Auditory adaptation in response to aging and psychosocial influences . Particular interest in the use of digital technology APPs, multisensory processing, hearing aids and non-invasive brain stimulation for the assessment or management of tinnitus and Neurosensory disorders.

 

Prof Russell Snell (Theme 2) - Molecular mechanisms of simple and complex neurodegenerative disorders, utilising knowledge of causal genes and their pathways to develop model systems to investigate the molecular pathogenesis of these disorders and screen for and test potential therapeutic agents. In particular, Huntington's disease, Alzheimer's disease, and Spinocerebellar ataxia. Genetic candidate screens looking for statistical association with DNA variation and disease in large human cohorts. Molecular methods to dissect disease mechanisms including tissue culture, proteomics, human tissue analysis, metabolomics, RNAseq and animal models (nematode worm model (C. elegans) of Alzheimer’s disease and sheep models of Huntington’s and Alzheimer’s disease). Analysis of exome and whole genome sequence with focus on neurodegenerative diseases of unknown cause, and Autism.

 

Assoc Prof Cathy Stinear (Theme 1, 3) - Neuro-rehabilitation, human neurophysiology and neural plasticity focused on translating neuroscience discoveries into clinical practice. Using neurophysiology and neuroimaging tools to accurately predict the potential for motor recovery after stroke for individual patients and testing a range of neuromodulation techniques including TMS for promoting neural plasticity and enhancing the effects of neuro-rehabilitation.

 

Assoc Prof Ben Thompson (Theme 3) - Plasticity in the visual areas of the human brain and how this plasticity can be harnessed to develop treatments for brain-based visual disorders using a variety of techniques to investigate human brain plasticity and visual cortex function including psychophysics, functional magnetic resonance imaging (fMRI), electroencephalography (EEG), transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). (Ben is now at the University of Waterloo, Canada)

 

Prof Peter Thorne (Theme 1, 3) - Interest in hearing and deafness.  A major focus on the mechanisms, treatment and prevention of sensorineural deafness due to cochlear injury, especially after noise exposure (noise-induced hearing loss) and with age, using animal models and clinical populations.  Approaches include molecular, anatomical and electrophysiological techniques to assess the inner ear, and systems to deliver and trial putative otoprotective compounds to the inner ear.  Interest in the use of imaging to investigate the cochlea and auditory pathways and have developed techniques to assess cochlear injury using MRI and to the study of inflammatory approaches associated with cochlear implantation using animal models.  Now applying these methods to assess the integrity of the blood-labyrinth barrier and development of inflammation in the human inner ear, especially with Meniere’s disease. Interest in the development of cochlear innervation and neurodegenerative changes in the auditory system associated with noise exposure and age and how these may relate to the development of cognitive impairment.  Collaborate on human population epidemiological and intervention studies around noise-induced hearing loss.

 

Assoc Prof Lynette Tippett (Theme 2, 4) - Understanding the clinical and neuropsychological effects of neurological disorders, and the neural bases of these effects with a strong emphasis on neurodegenerative disorders (particularly Huntington’s Disease, Alzheimer’s Disease and Motor Neuron Disease). The neural basis of cognitive functions, with a particular focus on memory, expertise (musical and computer-gaming) and effects of expertise on lateralisation of function: Methods include both behavioural and experimental paradigms and neuroimaging techniques (using a combination of DTI, fMRI and EEG).

 

Assoc Prof Srdjan Vlajkovic (Theme 1) - Cellular and molecular basis of cochlear homeostasis, and mechanisms of sensorineural hearing loss. Oxidative stress and inflammation in the development of noise-induced and age-related hearing loss. Purines (ATP and adenosine) involvement in cochlear physiology and the development of cochlear injury.

 

Assoc Prof Henry Waldvogel (Theme 1) - Chemical neuroanatomy of the human brain and changes that occur in neurodegenerative diseases particularly in Huntington's, Parkinson's, Motor Neuron and Alzheimer's disease; major interest in the inhibitory neurotransmitter receptors GABAA GABAB and glycine receptors and their associated proteins. Studies at both the regional and cellular level with high resolution light and confocal laser scanning microscopy. Animal models of Huntington's disease including the transgenic sheep model .

 

Assoc Prof Debbie Young (Theme 1, 3) - Use of adeno-associated viral (AAV) vector for gene therapy and generation of rodent models of PD, HD, AD, stroke and epilepsy.  Development of new gene regulation, cell targeting and gene editing tools for gene therapy. Development of antibody-based cognitive enhancers and therapies using immunisation and passive antibody transfer methods and behavioural testing in rats. Role of brain autoantibodies from human patients in disease pathogenesis and behaviour. Development of novel recombinant proteins for generation of therapeutic antibodies.

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Auckland District Health Board

BRNZ Auckland hospital

Dr Ed Mee (Theme 4) - Adult neurosurgery including cerebral vascular disease, brain tumours, epilepsy and trigeminal neuralgia. Particular interest in cervical radiculopathy and lumbar disc disease.

Dr Richard Roxburgh (Theme 2) - Neurologist with expertise in Neurogenetics and an interest in Huntington’s disease and neuromuscular disorders.

Assoc Prof Barry Snow (Theme 2, 3, 4) - Neurologist specialising in movement disorders such as Parkinson’s disease.

Dr Phil Wood (Theme 4) - Geriatric medicine specialist with an interest in mild cognitive impairment and Alzheimer’s disease.