Prevention, intervention & delivery

Another of our goals is to develop and build capacity for community outreach throughout New Zealand. We are committed to promoting clinical evaluation and implementation of preventative measures and early interventions; in order to minimise functional decline associated with brain ageing and ageing-related neurological disorders.



Cognitive declines associated with ageing and the progression of mild impairment to frank dementia are common problems across a variety of neurological disorders. Delaying the onset of dementia resonates with the  aims to prevent, improve outcome and reduce the burden of neurodegenerative and cerebrovascular disorders; delaying dementia onset by 5 years would reduce its prevalence by 50%. 

Lifestyle and risk factors for dementia and stroke explain a large amount of the variability in cohort studies of these devastating disorders. A number of interventions, such as risk factor modification, exercise, cognitive stimulation, behavioural therapy, and pharmacological treatments show promise in delaying mild cognitive impairment, progression to dementia and primary stroke prevention, but they need systematic study to validate their prospects as interventions in older populations.

A key benefit of this research is to facilitate representative samples and sufficiently powered designs to assess these interventions in neurological disorders such as AD, PD, HD and stroke. It is likely that the combination of active lifestyle, cognition-based therapy and risk management has the greatest chance of success.

Leadership Group

  • A. Prof Lynette Tippett
  • Prof John Dalrymple-Alford
  • Prof Valery Feigin
  • A. Prof Leigh Hale
  • Prof Ngaire Kerse
  • Dr Nick Cutfield

Clinical Leaders and Researchers: Prof Tim Anderson, Prof Toni Ashton, Prof Alan Barber, Assoc Prof Suzanne Barker-Collo, Dr Nick Cutfield, Prof John Dalrymple-Alford, Prof Valery Feigin, Assoc Prof Leigh Hale, Prof Ngaire Kerse, Prof Ian Kirk, Prof Rob Kydd, Dr Ping Liu, Dr Liana Machado, Prof Kathryn McPherson, Dr Edward Mee, Dr Tracy Melzer, Prof Pauline Norris, Prof Suzanne Purdy, Prof Ted Ruffman, Assoc Prof Barry Snow, Assoc Prof Lynette Tippett, Dr Phil Wood.